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NEW
PRINCIPLES OF COMPUTER PROCESSING
Entropy
and information in biological systems
In spite of enormous complexity of biological systems in general
and human in particular, the notion of entropy turns out to
be very useful in description of certain aspects of such objects.
As
first example we consider the following psychological experiment:
Suppose we have N lamps; and lamp number j flashes with probability
pj. The human should point out as quickly as possible which
lamp flashed. What is the mean time of human reaction if the
experiment is repeated many times?
The
answer turns out to be rather unexpected: the average reaction
time is proportional to the entropy (2.2) of our experiment
(and not to number of lamps N as one would naively think)
[Hyman R.,1953].
Moreover,
we can repeat the experiment under another conditions: we
can ask the human to point to the flashed lamp as soon very
quickly, such that sometimes he can even make mistakes. Then
we get two probabilistic experiments: experiment a, whose
outcomes are flashes of lamps, and experiment ß, whose
outcomes are human reactions. It turns out that the average
time of human reaction in this case is proportional to information
I( , ß)!
The
conclusion we can make from these experiments is that the
speed of signal propagation in human nerves is proportional
to mathematically well-defined amount of information contained
in the signal!
Another
indication of the relevance of entropy notion in biological
system is a well known fact that in any population of biological
species most of their physical characteristics (like say weight,
or length) have gaussian distribution density. As we know,
the gaussian distribution (2.18) maximises the entropy if
the dispersion is fixed. Therefore, we conclude that the principle
of maximal entropy (and also the constancy of dispersion)
has direct application to evolution of biological population!
Of
course, it seems very tempting to generalise the notion of
entropy and information to the level of biological objects,
or, say, mankind as a whole, looking at evolution of our civilisation,
or even the whole universe as huge random experiment. Such
attempts were made my many authors (see, for example, book
of Stonier [Stonier T., 1990]). Many authors these days speak
about "information field" as a fundamental field
of nature and so on. However, if we speak about total amount
of information (or entropy) contained in, say, human body,
or our whole civilisation, it is very difficult to explain
what do we mean. How to formulate the experiment explicitly?
Or, in thermodynamical terms, how to count all possible microscopic
states of the system? Which states should be considered to
be different? The problem is that, since the gap between the
level of civilisation and fundamental quantum level is very
big (in between we have chemical level, biological level,
social level...) it does not seem possible to give satisfactory
theoretical answer to this question at the moment.
Nevertheless,
taking mankind as a whole, or choosing one single human, it
is clear, as we can see from above examples, that the notion
of entropy can really be used for effective description of
certain aspects of their life. So maybe it is possible to
measure some characteristic of human experimentally, which
can be then satisfactorily interpreted as the "total
entropy of human being"? In the sequel we introduce such
variable. Then, based on the results of calculation of this
variable for different types of human, argue, that this variable
can really pretend to be a natural candidate for experimentally
measured human entropy, or "measure of human uncertainty".
We will referrer to the results of GDV experiments.
Statistical
interpretation of BEO-grams. BEO-entropy
To put the essentially qualitative discussion of the previous
section to more solid background one should choose one or
another mathematical approach for analysis of BEO-gram structure.
Ideally, we would like to have an algorithm which would allow
to distinguish between images which visually belong to essentially
different classes. It was demonstrated by numerous experiments
that [Korotkov K., 1998] these different classes, in turn,
describe essentially different human states. It was proposed
[Proceedings, 1999] the analyse of BEO-grams using so-called
"analysis of fractal dynamics", which allows to
encode the essential information carried by the image to relatively
small number of parameters (eight). This allows develop an
algorithm which effectively attribute images to different
classes.
Here
we present another approach to the same problem, based on
simplest possible probabilistic interpretation of BEO-gram
image. Namely, let us present the BEO-gram as a circular picture
having certain distribution of density along the radii. This
image may be presented as some function F(x) where x is an
angle within the interval [0,2 ].
Parameter F{x) may be different: for example, it may be the
maximum distance from the weight center of the BEO-gram to
the most distant point - max radii, or the average brightness
along the radii, or the distance to the median. In practice
we present calculations for a set of parameters.
As
we can see from many examples of BEO-grams, as a rule, function
F(x) is highly discontinuous. This suggests the idea to consider
function F(x) as random variable, and calculate associate
statistical parameters. Let us introduce the total brightness
parameter
and define new normalised function

Denote maximal and minimal values of function f(x) by fmin
and fmax respectively (see fig.???). Let us build a graph
P(f) of density distribution of values of function f(x) on
the interval [fmin, fmax] o Let us also introduce the normalised
distribution p(f) by the formula

Obviously function g(f) satisfies the normalisation condition
Now we are in position to introduce standard statistical characteristics:
the mean value fo, dispersion m1 and higher moments mj by
the formulas (2.15), (2.16).
The
entropy definition arising in this context is given by the
formula (2.17):

We
call entropy BEO
- the BEO-entropy.
Of course, the proposed statistical interpretation of function
F is some approximation to the real process only: in practice
there may be certain correlations between the amplitude at
different points (probably, there exist both short-range and
long-range correlations). Nevertheless, for us the main role
of BEO-entropy notion will be just practical: it will allow
to introduce natural classification of BEO-gram by "degree
of misbalance". Namely, for highly inhomogeneous BEO-grams
(which, according to experimental data in turn correspond
to unstable human state) the random variable F(x) has high
degree of uncertainty, which should lead to relatively high
value of BEO-entropy BEO.
In contrary, homogenous "quiet" BEO-grams correspond
to random variable F(x) with low degree of uncertainty, which
should give rise to relatively low values of BEO.
Results
of calculations of BEO-entropy eBEO presented in the next
section for different types of BEO-grams confirm importance
of this characteristic of BEO-gram. Moreover, we shall see
strong indications that variable eBEO is probably related
to the entropy of biological object discussed in above. Namely,
values of BEO
turn our to vary depending on age and state of human in exactly
the same way as we would expect.
Auto-correlation
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