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issue 33

Q & A about DHEA

What is DHEA?

DHEA (dehydroepiandrosterone) is a steroid hormone, produced primarily in the adrenal glands. Its daily production drops from 30 mg at age 20 to less than 6 mg at age 80. In just the past year (after Life Enhancement introduced DHEA to the market) it has become a popular topic in the news, the subject of several best-selling books, and a multimillion-dollar item in the supplement industry.

Why has it caught on so big?

Probably because the body of scientific research is so overwhelming. Then there is the fact that people almost always get a strong positive response when they try it. According to the studies, DHEA supplements may be able to increase your energy level, enhance your sex drive, improve your immunity to diseases (including cancer), reduce the ill effects of stress, enhance your memory and cognitive functions, decrease your body fat, and perhaps even extend your life.

What can I expect to feel?

Most people feel a substantial increase in energy level and well-being after a week or two. However, some people don't feel anything at all. If you don't have a noticeable subjective response, don't assume the DHEA isn't working. You are still likely to be getting benefits such as immune-system enhancement and long-term preventive effects. It is important, when embarking on a life-extension program, to set and hold your course to the future. It is important to ask, "How do I want to feel 10 years... or 20 years... or more... from today?"

What is the right dose?

According to leading researchers on DHEA, most people over 25 years old can take 25 to 50 mg of DHEA per day. That is the amount-when taken orally-that is apt to bring your DHEA back up to the level found in a healthy 25-year-old. Some women may need only 10 to 25 mg/day.

Can you summarize some of the most notable studies of DHEA?

bulletIn a key double-blind, placebo-controlled study by Dr. Samuel S. C. Yen of the University of San Diego, DHEA resulted in a "remarkable increase in perceived physical and psychological well-being for both men and women."
bulletWhen DHEA was given to middle-aged and older people with major depression and associated memory problems, the depression was relieved, and memory improved.
bulletIn several animal models, DHEA provided 100% protection against the potentially lethal effects of stress on the immune system. In humans, a recent study has shown that DHEA can significantly activate immune function, and that it has powerful immuno-enhancing properties.
bulletOther studies suggest that DHEA can block cancer during its early stages in animals. It has also been called the "ultimate antioxidant," because it disarms NADPH, the enzyme that activates carcinogens and generates oxygen free radicals.

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